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Cuando Gonzalo Pizarro se alz en el
2019-06-18
Cuando Gonzalo Pizarro se alzó en el Perú, nunca mostró intenciones de romper los vínculos que lo unían Physcion su rey, por mucho que su plan fuese establecer una monarquía, autónoma de la castellana, que gobernaría el territorio. En las misivas que envió al monarca, Pizarro confirmaba su obedienci
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Missed cases have been reported who
2019-06-18
Missed cases have been reported who had an initially elevated C5DC concentration that normalized on a repeated sample. Such a result may be caused by secondary carnitine depletion. To avoid carnitine depletion, we propose that the carnitine loading test be used to assist diagnosis of GA-1. Although,
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There were differentially expressed genes identified from th
2019-06-17
There were 3151 differentially expressed genes identified from the transcriptome profiling data of 497 patients (Fig. 2). Among these differentially expressed genes, 2190 genes were found to be upregulated in the group with infiltrating lymphocytes ≥1%. As shown in Table 2, these genes were enriched
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Fashions are dangerous things But it seems that global
2019-06-17
Fashions are dangerous things. But it DPQ seems that global health is no ephemeral trend. Every year, the field grows stronger. The Consortium of Universities for Global Health (CUGH) is a young organisation—its 2014 conference is only its fifth annual meeting. But in this short time, CUGH has esta
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In September countries agreed to the ambitious Sustainable D
2019-06-17
In September, 2015, 193 countries agreed to the ambitious Sustainable Development Goals (SDGs). SDG 3, for “healthy lives and wellbeing”, includes targets for universal health coverage (UHC). Some international commentators have raised questions about whether many of the SDGs are feasible and afford
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onde introduzimos a negritude como uma concep
2019-06-17
É onde introduzimos CCG-1423 negritude como uma concepção adotada pelos intelectuais e movimentos sociais ligados à causa negra no Brasil. A negritude foi conceituada por seu criador, o poeta e intelectual Aimé Cesairé, como “o simples reconhecimento do fato de ser negro, a aceitação de seu destino,
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br Materials and methods Eculizumab levels were measured
2019-06-17
Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)
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br Cholera remains a serious global public health problem
2019-06-17
Cholera remains a serious global public health problem, disproportionately affecting poor individuals, causing illness and death for thousands of people each year. Cholera cases are on the rise, with 47% more cases reported to WHO in 2014 than in 2013. Innovative approaches to control the disease
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It is important to know whether
2019-06-15
It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G
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br Diagnostic criteria Brugada syndrome is
2019-06-15
Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s
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br Case report A year old woman
2019-06-15
Case report A 58-year-old woman presented to our hospital with a history of several weeks of chronic dry cough and intermittent shortness of breath. On physical examination, the patient\'s blood pressure was 135/85 mmHg, oral temperature was 37.4 °C, pulse rate was 112/min, and her respiratory ra
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LQT can have numerous clinical manifestations
2019-06-15
LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise
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NAFLD and fatty liver is the accumulation of
2019-06-15
NAFLD and fatty liver is the accumulation of fat and cholesterol in hepatocytes. NAFLD is one of the most common liver diseases in the USA and worldwide. NAFLD is associated with obesity, inflammation and insulin resistance. Fat accumulation in the liver is due to the uptake and synthesis (intake) o
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Apesar de certo consenso em rela o necessidade de
2019-06-15
Apesar de certo consenso em relação à necessidade de construir táticas políticas, é preciso lembrar que boa parte das igrejas (neo) pentecostais foram elaboradas e se mantém com uma Sulfo-NHS-LC-Biotin organizacional diferente da estrutura centralizada e verticalizada da iurd. A estrutura organizac
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Desde ese ngulo es visible c mo la Antig edad
2019-06-14
Desde ese ángulo es visible cómo la Antigüedad vivía en la medida que era apropiada por los criollos: la gramática latina de Andrés Bello fue novedosa en cuanto explicó la lengua desde el castellano actual (y americano), con la conciencia que éste tenía una estructura distinta. Los símbolos grecorro
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