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One of the most prominent and serious side
2018-11-06
One of the most prominent and serious side effects of NSAIDs is occurrence of gastrointestinal damage (ulcerogenicity). Hence, it was necessary to test our compounds for their ulcerogenicity potential. In the present study, subacute treatment of TAPP (8mg/kg, p.o.) did not cause severe ulcerogenicit
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Among potential health beneficial effects in vitro assessmen
2018-11-06
Among potential health beneficial effects, in vitro assessment of fermented foods isolates for their hypocholesterolemic effect has been done by some researchers [16,31,45]. Cholesterol binding by LAB in the small intestine may reduce the amount of dietary cholesterol absorbed [31]. Several mechanis
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Whether calcium supplements can be beneficial
2018-11-06
Whether calcium supplements can be beneficial or harmful to the health of people is still controversial. Although the effects of calcium supplements or casual calcium uptake on health outcomes have been systematically reviewed [99], the risks of calcium supplements for cardiovascular diseases have n
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Since the Rad promoter contains
2018-11-06
Since the Rad51 promoter contains zolmitriptan for the E2F transcription factor, which is primarily active during entry of cells into S-phase (Bracken et al., 2004; Dyson, 1998; Shirodkar et al., 1992), one might expect that the proportion of the cell cycle spent in S-phase might account in part fo
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MicroRNAs miRNAs are small non coding
2018-11-06
MicroRNAs (miRNAs) are small non-coding RNAs which regulate gene expression in a post-transcriptional manner. A recent study reported that ZEB1, another EMT activator, can directly suppress the transcription of miR-141, miR-200c, and miR-203 by interacting with their respective promoter regions. Mor
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To assess the applicability of
2018-11-06
To assess the applicability of our method, we selected three binary-fate stem cell differentiation systems for which high-quality single-cell gene expression data are available. These examples include the differentiation of inner cell mass (ICM) into either primitive endoderm (PE) or epiblast (EPI)
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Introduction The stem cell subset contained within the bone
2018-11-06
Introduction The stem cell subset contained within the bone marrow stromal cell population (BMSCs, also known as bone marrow-derived mesenchymal stem cells) is characterized by self-renewal capacity, clonogenicity in vitro, multipotent differentiation into mesoderm-type purchase SL-327 including o
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br The adult subventricular zone a source of neural
2018-11-06
The adult subventricular zone: a source of neural stem cells The SVZ is the main reservoir of neural stem cells (NSCs) in the adult mammalian Tenovin-6 (Doetsch et al., 1997; Quinones-Hinojosa et al., 2006; Sanai et al., 2004). It is widely accepted that NSCs correspond to a pool of astroglial ce
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Similar to our in vitro results
2018-11-06
Similar to our in vitro results, transplanted iNSCs exhibited in vivo-characteristics, transcriptome profiles, neural and metabolic programs similar to those of transplanted NSCs. In contrast to engrafted forebrain NSCs, however, transplanted iNSCs strongly expressed caudal regional marker genes and
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Sca expression has earlier been shown
2018-11-06
Sca-1 expression has earlier been shown to mark order Batimastat with poor CFE (Jensen et al., 2008; Jensen et al., 2009). We can now for the first time show that a PletA6Sca is a highly proliferative subpopulation of Plet-1pos cells that displays almost as efficient colony forming efficiency as A6
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Recently work has been focused on the adipose tissue
2018-11-06
Recently, work has been focused on the adipose tissue-derived stromal cell (ASCs) population, since retrieval is straight forward and non-harmful coupled to low-risk surgical procedures. However, biological properties of ASCs have only been assessed by indiscriminate isolation from mostly white fat
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The expression of neurotrophic or angiogenic
2018-11-06
The expression of neurotrophic or angiogenic proteins by grafted neural paricalcitol benefits the two types of transplanted progenitors in the infarct core. First, BDNF, which is known to be neuroprotective (Louhivuori et al., 2011), may ensure the survival of newly formed neurons during the first
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Global gene expression of RB null teratomas revealed an
2018-11-05
Global gene expression of RB1-null teratomas revealed an upregulation of neural-related genes and a depleted expression of epidermal tissue-related genes. As both the nervous system and the epidermis originate from the ectoderm, these results suggest that the RB1 ablation could alter early ectoderma
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In these distributions the main diffraction peaks with
2018-11-05
In these distributions the main diffraction peaks (with integer indices) are clearly visible as well as peaks with non-integer indices. The onset of the latter is associated with the modulation [6] mentioned above. The principal diffraction peaks can be indexed in the tetragonal unit cell with a lat
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The scheme of our experimental
2018-11-05
The scheme of our experimental setup is shown in Fig. 1. The preselected pkc inhibitor beam (the beam size is about 3cm×1cm), reflected by the mosaic crystal of pyrolytic graphite (PG) with reflecting plane (002), falls on the monochromator K1 made from perfect quartz crystal. Reflected by K1 highl
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