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miRNAs are known to regulate the expression of multiple targ
2018-11-08

miRNAs are known to regulate the expression of multiple targets via binding to 3′ UTR. Our finding that the miR-29 family regulates global DNA methylation and demethylation adds another role to the list of common regulatory roles of miRNAs. The miR-29 family was known to regulate ECM proteins in phy
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miRNAs often take part in fine tuning major signaling pathwa
2018-11-07

miRNAs often take part in fine-tuning major signaling pathways (Inui et al., 2010). The interaction between Notch signaling and an miRNA, namely miR-9a, was first described in Drosophila in the context of sensory organ precursor development (Li et al., 2006). More recently, the existence of an inter
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br Introduction Newborn neurons are
2018-11-07

Introduction Newborn neurons are continuously generated throughout life in several areas of the mammalian brain, including the subgranular zone (SGZ) of the hippocampal dentate gyrus (Imayoshi et al., 2008; Palmer et al., 1997; Zhao et al., 2008). Adult hippocampal neurogenesis is essential for n
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Ara jo et al highlights that the progressive
2018-11-07

Araújo et al. (1992) highlights that the progressive targeting of the Brazilian MT exports in the late 1980s towards developed countries such as USA, Germany, Italy and Canada shows that the industry made a significant competitive effort. The growth of the intra-industry trade, the diversification
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The diagnosis of OSAS is one of the
2018-11-07

The diagnosis of OSAS is one of the key problems in this field. Although polysomnography is considered as the gold standard for the diagnosis of OSAS [1], this method is not yet widely available due, probably, to its high cost. Thus, some attempts have been made to develop self-report measures based
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There is evidence of an
2018-11-07

There is evidence of an association between bruxism and tension, stress, and emotional disturbance [33]; however the influence of socioeconomic status is less clear [4,25]. Of note, our study showed that the presence of bruxism was associated with higher income and socioeconomic class as well as inc
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Con el n mero de la revista
2018-11-07

Con el número 395 de la revista concluimos un año más de publicar temas económicos coyunturales de actualidad. Así, iniciamos con Carlos Guerrero de Lizardi, mediante un análisis de “Un enfoque imperfecto para medir la distribución de la riqueza financiera y no financiera de los hogares en México 1
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HLA transgenic mice are widely used to model the human
2018-11-07

HLA-transgenic mice are widely used to model the human T cell response in mice. We focused the present study on the HLA B*0702 allele, which is associated with strong T cell response in terms of magnitude and breath (Weiskopf et al., 2013), thereby allowing us to test the role of multiple cross-reac
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We also compared protein abundances
2018-11-07

We also compared protein abundances in primary Merlin-deficient human meningioma leukotriene against human meningeal cells, and primary human schwannoma cells against primary human Schwann cells. We identified numerous novel upregulated and downregulated proteins and phospho-proteins, performed Gen
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nop receptor br Materials and Methods br Results br
2018-11-07

Materials and Methods Results Discussion Investigations by our group and others have shown differential expression of host genes at the RNA level in peripheral blood in response to ARV infections (Ramilo et al., 2007; Zaas et al., 2009; Woods et al., 2013; Zaas et al., 2013), with heavy rep
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Since Tnmd KO mice harbor very mild
2018-11-07

Since Tnmd KO mice harbor very mild developmental changes, including interesting ultrastructural phenotype characterized by irregular and thicker collagen I fibrils when examined by electron microscopy (Docheva et al., 2005), we hypothesized possible structural and biomechanical alterations of the t
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Cofilin partners with the Arp and WAVE complex to
2018-11-07

Cofilin 1 partners with the Arp2/3 and WAVE complex to stimulate the formation of dendritic actin, which is an essential step for cell protrusion and invasion (Ichetovkin et al., 2002; Desmarais et al., 2005; Beaty and Condeelis, 2014; Bravo-Cordero et al., 2013). Both pathways are activated by the
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A recent report by Chen
2018-11-07

A recent report by Chen-Scarabelli et al. describes a timely study that employed perfused isolated rabbit hearts and aortic tissue strips to assess the effect of acute administration of CFZ on coronary resistance, vascular tone and reactivity (). Their experiments revealed that acute perfusion of C
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br Search Strategy and Selection Criteria
2018-11-07

Search Strategy and Selection Criteria Conflicts of Interest Acknowledgments Introduction Chronological age is a major risk factor for functional impairments, chronic diseases and mortality. However, there is still great heterogeneity in the health outcomes of older individuals (Lowsky e
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br Data sets and attributes The
2018-11-07

Data sets and attributes The data published here are organized in two ‘csv’ files, ‘rawdata.csv.gz’ (4.5MB) and ‘features.csv’ (200kB). The raw data are stored in the first file ‘rawdata.csv.gz’, where each line represents a single measurement per sensor. Consequently, one needs to read specific
 
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